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Recent insights into mechanisms preventing ectopic centromere formation

The centromere is a specialized chromosomal structure essential for chromosome segregation. Centromere dysfunction leads to chromosome segregation errors and genome instability. In most eukaryotes, centromere identity is specified epigenetically by CENP-A, a centromere-specific histone H3 variant. C...

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Detalles Bibliográficos
Autores principales: Dong, Qianhua, Yang, Jinpu, Gao, Jinxin, Li, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424319/
https://www.ncbi.nlm.nih.gov/pubmed/34493071
http://dx.doi.org/10.1098/rsob.210189