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CG7379 and ING1 suppress cancer cell invasion by maintaining cell–cell junction integrity

Approximately 90% of cancer-related deaths can be attributed to a tumour's ability to spread. We have identified CG7379, the fly orthologue of human ING1, as a potent invasion suppressor. ING1 is a type II tumour suppressor with well-established roles in the transcriptional regulation of genes...

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Detalles Bibliográficos
Autores principales: Rusu, Alexandra D., Cornhill, Zoe E., Coutiño, Brenda Canales, Uribe, Marcos Castellanos, Lourdusamy, Anbarasu, Markus, Zsuzsa, May, Sean T., Rahman, Ruman, Georgiou, Marios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424350/
https://www.ncbi.nlm.nih.gov/pubmed/34493070
http://dx.doi.org/10.1098/rsob.210077