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CG7379 and ING1 suppress cancer cell invasion by maintaining cell–cell junction integrity
Approximately 90% of cancer-related deaths can be attributed to a tumour's ability to spread. We have identified CG7379, the fly orthologue of human ING1, as a potent invasion suppressor. ING1 is a type II tumour suppressor with well-established roles in the transcriptional regulation of genes...
Autores principales: | Rusu, Alexandra D., Cornhill, Zoe E., Coutiño, Brenda Canales, Uribe, Marcos Castellanos, Lourdusamy, Anbarasu, Markus, Zsuzsa, May, Sean T., Rahman, Ruman, Georgiou, Marios |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424350/ https://www.ncbi.nlm.nih.gov/pubmed/34493070 http://dx.doi.org/10.1098/rsob.210077 |
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