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Liquid chromatography-mass spectrometry method for the quantification of an anti-sclerostin monoclonal antibody in cynomolgus monkey serum

Liquid chromatography tandem mass spectrometry (LC-MS/MS) has gradually become a promising alternative to ligand binding assay for the bioanalysis of biotherapeutic molecules, due to its rapid method development and high accuracy. In this study, we established a new LC-MS/MS method for the determina...

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Detalles Bibliográficos
Autores principales: Gao, Yuxiong, Chen, Zhendong, Yang, Changyong, Zhong, Dafang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424367/
https://www.ncbi.nlm.nih.gov/pubmed/34513123
http://dx.doi.org/10.1016/j.jpha.2020.08.005