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Comparative permeability of three saikosaponins and corresponding saikogenins in Caco-2 model by a validated UHPLC-MS/MS method

Saikosaponins (SSs) are the main active components extracted from Bupleuri Radix (BR) which has been used as an important herbal drug in Asian countries for thousands of years. It has been reported that the intestinal bacteria plays an important role in the in vivo disposal of oral SSs. Although the...

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Detalles Bibliográficos
Autores principales: Ren, Siqi, Liu, Jingjing, Xue, Yunwen, Zhang, Mei, Liu, Qiwei, Xu, Jie, Zhang, Zunjian, Song, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424369/
https://www.ncbi.nlm.nih.gov/pubmed/34513119
http://dx.doi.org/10.1016/j.jpha.2020.06.006