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A SHHecret target of relapsed medulloblastoma: Astrocytes

In this issue of JEM, Guo et al. (2021. J. Exp. Med. https://doi.org/10.1084/jem.20202350) examine the importance of tumor-derived astrocytes in SHH-medulloblastoma recurrence. They show that tumor cells transdifferentiate to tumor-derived astrocytes via bone morphogenetic proteins and Sox9, which e...

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Detalles Bibliográficos
Autores principales: Qadeer, Zulekha A., Weiss, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424466/
https://www.ncbi.nlm.nih.gov/pubmed/34398189
http://dx.doi.org/10.1084/jem.20211141