A SHHecret target of relapsed medulloblastoma: Astrocytes
In this issue of JEM, Guo et al. (2021. J. Exp. Med. https://doi.org/10.1084/jem.20202350) examine the importance of tumor-derived astrocytes in SHH-medulloblastoma recurrence. They show that tumor cells transdifferentiate to tumor-derived astrocytes via bone morphogenetic proteins and Sox9, which e...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424466/ https://www.ncbi.nlm.nih.gov/pubmed/34398189 http://dx.doi.org/10.1084/jem.20211141 |