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Targeted RNA Sequencing of Formalin-Fixed, Paraffin-Embedded Temporal Arteries From Giant Cell Arteritis Cases Reveals Viral Signatures

BACKGROUND AND OBJECTIVES: Varicella zoster virus (VZV) antigen has been detected in temporal arteries (TAs) of individuals with giant cell arteritis (GCA), the most common systemic vasculitis in older adults. Thus, we explored the contribution of VZV to GCA pathogenesis. METHODS: Formalin-fixed, pa...

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Detalles Bibliográficos
Autores principales: Bubak, Andrew N., Mescher, Teresa, Mariani, Michael, Frietze, Seth E., Hassell, James E., Niemeyer, Christy S., Como, Christina N., Burnet, Anna M., Subramanian, Prem S., Cohrs, Randall J., Mahalingam, Ravi, Nagel, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424492/
https://www.ncbi.nlm.nih.gov/pubmed/34493606
http://dx.doi.org/10.1212/NXI.0000000000001078