Feedback repression of PPARα signaling by Let-7 microRNA

Peroxisome proliferator-activated receptor α (PPARα) controls hepatic lipid homeostasis and is the target of lipid-lowering fibrate drugs. PPARα activation represses expression of let-7 microRNA (miRNA), but the function of let-7 in PPARα signaling and lipid metabolism is unknown. In the current stu...

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Detalles Bibliográficos
Autores principales: Yagai, Tomoki, Yan, Tingting, Luo, Yuhong, Takahashi, Shogo, Aibara, Daisuke, Kim, Donghwan, Brocker, Chad N., Levi, Moshe, Motohashi, Hozumi, Gonzalez, Frank J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424520/
https://www.ncbi.nlm.nih.gov/pubmed/34380035
http://dx.doi.org/10.1016/j.celrep.2021.109506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424520/
https://www.ncbi.nlm.nih.gov/pubmed/34380035
http://dx.doi.org/10.1016/j.celrep.2021.109506

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