Non-uniformity of Changes in Drug-Metabolizing Enzymes and Transporters in Liver Cirrhosis: Implications for Drug Dosage Adjustment

[Image: see text] Liver cirrhosis is a chronic disease that affects the liver structure, protein expression, and overall metabolic function. Abundance data for drug-metabolizing enzymes and transporters (DMET) across all stages of disease severity are scarce. Levels of these proteins are crucial for...

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Detalles Bibliográficos
Autores principales: El-Khateeb, Eman, Achour, Brahim, Al-Majdoub, Zubida M., Barber, Jill, Rostami-Hodjegan, Amin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424631/
https://www.ncbi.nlm.nih.gov/pubmed/34428046
http://dx.doi.org/10.1021/acs.molpharmaceut.1c00462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424631/
https://www.ncbi.nlm.nih.gov/pubmed/34428046
http://dx.doi.org/10.1021/acs.molpharmaceut.1c00462

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