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[(18)F]Atorvastatin Pharmacokinetics and Biodistribution in Healthy Female and Male Rats

[Image: see text] Statins are 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors that are widely used to prevent cardiovascular diseases. However, a series of pleiotropic mechanisms have been associated with statins, particularly with atorvastatin. Therefore, the assessment of [(18)F]atorvas...

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Detalles Bibliográficos
Autores principales: Clemente, Gonçalo S., Antunes, Inês F., Sijbesma, Jürgen W. A., van Waarde, Aren, Lammertsma, Adriaan A., Dömling, Alexander, Elsinga, Philip H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424645/
https://www.ncbi.nlm.nih.gov/pubmed/34351158
http://dx.doi.org/10.1021/acs.molpharmaceut.1c00305