Long-term depression links amyloid-β to the pathological hyperphosphorylation of tau

In Alzheimer’s disease, soluble oligomers of the amyloid-β peptide (Aβ(o)) trigger a cascade of events that includes abnormal hyperphosphorylation of the protein tau, which is essential for pathogenesis. However, the mechanistic link between these two key pathological proteins remains unclear. Using...

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Detalles Bibliográficos
Autores principales: Taylor, Henry B.C., Emptage, Nigel J., Jeans, Alexander F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424646/
https://www.ncbi.nlm.nih.gov/pubmed/34469725
http://dx.doi.org/10.1016/j.celrep.2021.109638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424646/
https://www.ncbi.nlm.nih.gov/pubmed/34469725
http://dx.doi.org/10.1016/j.celrep.2021.109638

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