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Activation Pathways and Free Energy Landscapes of the SARS-CoV-2 Spike Protein

[Image: see text] Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses a spike protein (S-protein) to recognize the receptor protein ACE2 of human cells and initiate infection, during which the conformational transition of the S-protein from inactive (down) state to active (up) state is...

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Detalles Bibliográficos
Autores principales: Wu, Yichao, Qian, Ruixin, Yang, Yan, Sheng, Yuebiao, Li, Wenfei, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424691/
https://www.ncbi.nlm.nih.gov/pubmed/34514271
http://dx.doi.org/10.1021/acsomega.1c03384