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Loss of signal transducer and activator of transcription 3 impaired the osteogenesis of mesenchymal progenitor cells in vivo and in vitro

BACKGROUND: Signal transducer and activator of transcription 3 (Stat3) is a cytoplasmic transcription factor that participates in various biologic processes. Loss of Stat3 causes hyperimmunoglobulin E syndrome, presenting with skeletal disorders including osteoporosis, recurrent fractures, scoliosis...

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Detalles Bibliográficos
Autores principales: Huang, Zijing, Feng, Jingyi, Feng, Xin, Chan, Laiting, Lu, Jiarui, Lei, Lizhen, Huang, Zhuwei, Zhang, Xiaolei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424822/
https://www.ncbi.nlm.nih.gov/pubmed/34496957
http://dx.doi.org/10.1186/s13578-021-00685-3