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Loss of signal transducer and activator of transcription 3 impaired the osteogenesis of mesenchymal progenitor cells in vivo and in vitro
BACKGROUND: Signal transducer and activator of transcription 3 (Stat3) is a cytoplasmic transcription factor that participates in various biologic processes. Loss of Stat3 causes hyperimmunoglobulin E syndrome, presenting with skeletal disorders including osteoporosis, recurrent fractures, scoliosis...
Autores principales: | Huang, Zijing, Feng, Jingyi, Feng, Xin, Chan, Laiting, Lu, Jiarui, Lei, Lizhen, Huang, Zhuwei, Zhang, Xiaolei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424822/ https://www.ncbi.nlm.nih.gov/pubmed/34496957 http://dx.doi.org/10.1186/s13578-021-00685-3 |
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