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Exosomal ERp44 derived from ER-stressed cells strengthens cisplatin resistance of nasopharyngeal carcinoma

BACKGROUND: Nasopharyngeal carcinoma (NPC) is one of the most common malignancies in head and neck. Platinum-based chemotherapy is an important treatment for NPC. However, the molecular mechanism of resistance to platinum drug remains unknown. Endoplasmic reticulum resident protein 44(ERp44), an unf...

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Detalles Bibliográficos
Autores principales: Xia, Tian, Tian, Hui, Zhang, Kaiwen, Zhang, Siyu, Chen, Wenhui, Shi, Si, You, Yiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424889/
https://www.ncbi.nlm.nih.gov/pubmed/34493236
http://dx.doi.org/10.1186/s12885-021-08712-9