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CircMYH9 drives colorectal cancer growth by regulating serine metabolism and redox homeostasis in a p53-dependent manner

BACKGROUND: Circular RNAs (circRNAs) play important roles in cancer progression and metabolism regulation. Serine/glycine metabolism supports the growth of cancer cells by contributing to their anabolic demands and epigenome as well as by regulating their redox state. However, the role of circRNA in...

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Detalles Bibliográficos
Autores principales: Liu, Xin, Liu, Yunze, Liu, Zhao, Lin, Changwei, Meng, Fanchao, Xu, Lei, Zhang, Xiuzhong, Zhang, Chong, Zhang, Penbo, Gong, Shuai, Wu, Nai, Ren, Zeqiang, Song, Jun, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424912/
https://www.ncbi.nlm.nih.gov/pubmed/34496888
http://dx.doi.org/10.1186/s12943-021-01412-9