Cargando…

Dendritic cells matured with recombinant human sperm associated antigen 9 (rhSPAG9) induce CD4(+), CD8(+) T cells and activate NK cells: a potential candidate molecule for immunotherapy in cervical cancer

BACKGROUND: Dendritic cell (DC)-based immunotherapy is capable of activating the immune system and in particular tumor-specific cytotoxic T lymphocytes (CTLs) to eradicate the tumor. However, major limitations are the availability of autologous tumor cells as antigenic source and the selection of an...

Descripción completa

Detalles Bibliográficos
Autores principales: Dhandapani, Hemavathi, Jayakumar, Hascitha, Seetharaman, Abirami, Singh, Shirley Sunder, Ganeshrajah, Selvaluxmy, Jagadish, Nirmala, Suri, Anil, Thangarajan, Rajkumar, Ramanathan, Priya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424976/
https://www.ncbi.nlm.nih.gov/pubmed/34493268
http://dx.doi.org/10.1186/s12935-021-01951-7