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Dendritic cells matured with recombinant human sperm associated antigen 9 (rhSPAG9) induce CD4(+), CD8(+) T cells and activate NK cells: a potential candidate molecule for immunotherapy in cervical cancer
BACKGROUND: Dendritic cell (DC)-based immunotherapy is capable of activating the immune system and in particular tumor-specific cytotoxic T lymphocytes (CTLs) to eradicate the tumor. However, major limitations are the availability of autologous tumor cells as antigenic source and the selection of an...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424976/ https://www.ncbi.nlm.nih.gov/pubmed/34493268 http://dx.doi.org/10.1186/s12935-021-01951-7 |