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Multivalent electrostatic pi–cation interaction between synaptophysin and synapsin is responsible for the coacervation

We recently showed that synaptophysin (Syph) and synapsin (Syn) can induce liquid–liquid phase separation (LLPS) to cluster small synaptic-like microvesicles in living cells which are highly reminiscent of SV cluster. However, as there is no physical interaction between them, the underlying mechanis...

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Detalles Bibliográficos
Autores principales: Kim, Goeun, Lee, Sang-Eun, Jeong, Seonyoung, Lee, Jeongkun, Park, Daehun, Chang, Sunghoe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424992/
https://www.ncbi.nlm.nih.gov/pubmed/34496937
http://dx.doi.org/10.1186/s13041-021-00846-y