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Multivalent electrostatic pi–cation interaction between synaptophysin and synapsin is responsible for the coacervation
We recently showed that synaptophysin (Syph) and synapsin (Syn) can induce liquid–liquid phase separation (LLPS) to cluster small synaptic-like microvesicles in living cells which are highly reminiscent of SV cluster. However, as there is no physical interaction between them, the underlying mechanis...
Autores principales: | Kim, Goeun, Lee, Sang-Eun, Jeong, Seonyoung, Lee, Jeongkun, Park, Daehun, Chang, Sunghoe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424992/ https://www.ncbi.nlm.nih.gov/pubmed/34496937 http://dx.doi.org/10.1186/s13041-021-00846-y |
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