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A novel automated image analysis pipeline for quantifying morphological changes to the endoplasmic reticulum in cultured human cells

BACKGROUND: In mammalian cells the endoplasmic reticulum (ER) comprises a highly complex reticular morphology that is spread throughout the cytoplasm. This organelle is of particular interest to biologists, as its dysfunction is associated with numerous diseases, which often manifest themselves as c...

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Detalles Bibliográficos
Autores principales: Garcia-Pardo, M. Elena, Simpson, Jeremy C., O’Sullivan, Niamh C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425006/
https://www.ncbi.nlm.nih.gov/pubmed/34496765
http://dx.doi.org/10.1186/s12859-021-04334-x