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An iteration model for identifying essential proteins by combining comprehensive PPI network with biological information

BACKGROUND: Essential proteins have great impacts on cell survival and development, and played important roles in disease analysis and new drug design. However, since it is inefficient and costly to identify essential proteins by using biological experiments, then there is an urgent need for automat...

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Detalles Bibliográficos
Autores principales: Li, Shiyuan, Zhang, Zhen, Li, Xueyong, Tan, Yihong, Wang, Lei, Chen, Zhiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425031/
https://www.ncbi.nlm.nih.gov/pubmed/34496745
http://dx.doi.org/10.1186/s12859-021-04300-7