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An iteration model for identifying essential proteins by combining comprehensive PPI network with biological information
BACKGROUND: Essential proteins have great impacts on cell survival and development, and played important roles in disease analysis and new drug design. However, since it is inefficient and costly to identify essential proteins by using biological experiments, then there is an urgent need for automat...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425031/ https://www.ncbi.nlm.nih.gov/pubmed/34496745 http://dx.doi.org/10.1186/s12859-021-04300-7 |