Insuline-Like Growth Factor-2 (IGF2) and Hepatocyte Growth Factor (HGF) Promote Lymphomagenesis in p53-null Mice in Tissue-specific and Estrogen-signaling Dependent Manners

Background:Trp53(-/-) mice are prone to develop lymphomas at old ages. Factors promoting this tumorigenesis are unknown. Here, we showed human ovulatory follicular fluid (FF) largely promotes lymphomagenesis in Trp53(-/-)mice at earlier ages. Meanwhile, we clarified that IGF2 and HGF are important c...

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Detalles Bibliográficos
Autores principales: Huang, Hsuan-Shun, Chu, Sung-Chao, Chen, Pao-Chu, Lee, Ming-Hsun, Huang, Chi-Ya, Chou, Hsien-ming, Chu, Tang-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425200/
https://www.ncbi.nlm.nih.gov/pubmed/34539876
http://dx.doi.org/10.7150/jca.60120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425200/
https://www.ncbi.nlm.nih.gov/pubmed/34539876
http://dx.doi.org/10.7150/jca.60120

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