PCSK9 immunization using nanoliposomes: preventive efficacy against hypercholesterolemia and atherosclerosis

INTRODUCTION: The aim of the study was to study a nanoliposomal anti-PCSK9 vaccine as a novel approach for cholesterol lowering via PCSK9 inhibition. MATERIAL AND METHODS: An immunogenic peptide construct termed immunogenic fused PCSK9-tetanus (IFPT) was displayed on the surface of liposome nanopart...

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Detalles Bibliográficos
Autores principales: Momtazi-Borojeni, Amir Abbas, Jaafari, Mahmoud Reza, Afshar, Mohammad, Banach, Maciej, Sahebkar, Amirhossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2021
Materias:
Experimental Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425258/
https://www.ncbi.nlm.nih.gov/pubmed/34522266
http://dx.doi.org/10.5114/aoms/133885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425258/
https://www.ncbi.nlm.nih.gov/pubmed/34522266
http://dx.doi.org/10.5114/aoms/133885

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