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PCSK9 immunization using nanoliposomes: preventive efficacy against hypercholesterolemia and atherosclerosis
INTRODUCTION: The aim of the study was to study a nanoliposomal anti-PCSK9 vaccine as a novel approach for cholesterol lowering via PCSK9 inhibition. MATERIAL AND METHODS: An immunogenic peptide construct termed immunogenic fused PCSK9-tetanus (IFPT) was displayed on the surface of liposome nanopart...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Termedia Publishing House
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425258/ https://www.ncbi.nlm.nih.gov/pubmed/34522266 http://dx.doi.org/10.5114/aoms/133885 |