Chromosomal aberrations after induced pluripotent stem cells reprogramming

Induced pluripotent stem cells (iPSCs) are generated from adult cells that have been reprogrammed to pluripotency. However, in vitro cultivation and genetic reprogramming increase genetic instability, which could result in chromosomal abnormalities. Maintenance of genetic stability after reprogrammi...

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Detalles Bibliográficos
Autores principales: Vaz, Isadora May, Borgonovo, Tamara, Kasai-Brunswick, Tais Hanae, dos Santos, Danúbia Silva, Mesquita, Fernanda Cristina Paccola, Vasques, Juliana Ferreira, Gubert, Fernanda, Rebelatto, Carmen Lúcia Kuniyoshi, Senegaglia, Alexandra Cristina, Brofman, Paulo Roberto Slud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2021
Materias:
Human and Medical Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425414/
https://www.ncbi.nlm.nih.gov/pubmed/34496008
http://dx.doi.org/10.1590/1678-4685-GMB-2020-0147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425414/
https://www.ncbi.nlm.nih.gov/pubmed/34496008
http://dx.doi.org/10.1590/1678-4685-GMB-2020-0147

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