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Inflated false discovery rate due to volcano plots: problem and solutions

MOTIVATION: Volcano plots are used to select the most interesting discoveries when too many discoveries remain after application of Benjamini–Hochberg’s procedure (BH). The volcano plot suggests a double filtering procedure that selects features with both small adjusted [Formula: see text]-value and...

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Detalles Bibliográficos
Autores principales: Ebrahimpoor, Mitra, Goeman, Jelle J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425469/
https://www.ncbi.nlm.nih.gov/pubmed/33758907
http://dx.doi.org/10.1093/bib/bbab053