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Less is more: Biased loss of CpG dinucleotides strengthens antiviral immunity

Viruses may not only affect our daily lives but also shape our genome evolution. A recent study shows that the zinc-finger antiviral protein (ZAP) drives CpG suppression in a biased manner. Genes involved in the defense against viral invaders are particularly CpG suppressed to avoid self-targeting a...

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Detalles Bibliográficos
Autores principales: Sauter, Daniel, Kirchhoff, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425523/
https://www.ncbi.nlm.nih.gov/pubmed/34495970
http://dx.doi.org/10.1371/journal.pbio.3001353