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Less is more: Biased loss of CpG dinucleotides strengthens antiviral immunity
Viruses may not only affect our daily lives but also shape our genome evolution. A recent study shows that the zinc-finger antiviral protein (ZAP) drives CpG suppression in a biased manner. Genes involved in the defense against viral invaders are particularly CpG suppressed to avoid self-targeting a...
Autores principales: | Sauter, Daniel, Kirchhoff, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425523/ https://www.ncbi.nlm.nih.gov/pubmed/34495970 http://dx.doi.org/10.1371/journal.pbio.3001353 |
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