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Using machine learning and big data to explore the drug resistance landscape in HIV

Drug resistance mutations (DRMs) appear in HIV under treatment pressure. DRMs are commonly transmitted to naive patients. The standard approach to reveal new DRMs is to test for significant frequency differences of mutations between treated and naive patients. However, we then consider each mutation...

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Detalles Bibliográficos
Autores principales: Blassel, Luc, Tostevin, Anna, Villabona-Arenas, Christian Julian, Peeters, Martine, Hué, Stéphane, Gascuel, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425536/
https://www.ncbi.nlm.nih.gov/pubmed/34437532
http://dx.doi.org/10.1371/journal.pcbi.1008873