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ngsComposer: an automated pipeline for empirically based NGS data quality filtering

Next-generation sequencing (NGS) enables massively parallel acquisition of large-scale omics data; however, objective data quality filtering parameters are lacking. Although a useful metric, evidence reveals that platform-generated Phred values overestimate per-base quality scores. We have developed...

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Detalles Bibliográficos
Autores principales: Kuster, Ryan D, Yencho, G Craig, Olukolu, Bode A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425578/
https://www.ncbi.nlm.nih.gov/pubmed/33822850
http://dx.doi.org/10.1093/bib/bbab092