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IDH Mutation Subgroup Status Associates with Intratumor Heterogeneity and the Tumor Microenvironment in Intrahepatic Cholangiocarcinoma

Intrahepatic cholangiocarcinoma (ICC) is highly heterogeneous. Here, the authors perform exome sequencing and bulk RNA sequencing on 73 tumor regions from 14 ICC patients to portray the multi‐faceted intratumor heterogeneity (ITH) landscape of ICC. The authors show that ITH is highly concordant acro...

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Detalles Bibliográficos
Autores principales: Xiang, Xiao, Liu, Ziyang, Zhang, Chong, Li, Zhao, Gao, Jie, Zhang, Changkun, Cao, Qi, Cheng, Jinghui, Liu, Hengkang, Chen, Dingbao, Cheng, Qian, Zhang, Ning, Xue, Ruidong, Bai, Fan, Zhu, Jiye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425914/
https://www.ncbi.nlm.nih.gov/pubmed/34250753
http://dx.doi.org/10.1002/advs.202101230