Near Complete Repair After Myocardial Infarction in Adult Mice by Altering the Inflammatory Response With Intramyocardial Injection of α-Gal Nanoparticles

Background: Neonatal mice, but not older mice, can regenerate their hearts after myocardial-infarction (MI), a process mediated by pro-reparative macrophages. α-Gal nanoparticles applied to skin wounds in adult-mice bind the anti-Gal antibody, activate the complement cascade and generate complement...

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Detalles Bibliográficos
Autores principales: Galili, Uri, Zhu, Zhongkai, Chen, Jiwang, Goldufsky, Josef W., Schaer, Gary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425953/
https://www.ncbi.nlm.nih.gov/pubmed/34513957
http://dx.doi.org/10.3389/fcvm.2021.719160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425953/
https://www.ncbi.nlm.nih.gov/pubmed/34513957
http://dx.doi.org/10.3389/fcvm.2021.719160

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