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Near Complete Repair After Myocardial Infarction in Adult Mice by Altering the Inflammatory Response With Intramyocardial Injection of α-Gal Nanoparticles
Background: Neonatal mice, but not older mice, can regenerate their hearts after myocardial-infarction (MI), a process mediated by pro-reparative macrophages. α-Gal nanoparticles applied to skin wounds in adult-mice bind the anti-Gal antibody, activate the complement cascade and generate complement...
Autores principales: | Galili, Uri, Zhu, Zhongkai, Chen, Jiwang, Goldufsky, Josef W., Schaer, Gary L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425953/ https://www.ncbi.nlm.nih.gov/pubmed/34513957 http://dx.doi.org/10.3389/fcvm.2021.719160 |
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