Heat But Not Mechanical Hypersensitivity Depends on Voltage-Gated Ca(V)2.2 Calcium Channel Activity in Peripheral Axon Terminals Innervating Skin

Voltage-gated Ca(V)2.2 calcium channels are expressed in nociceptors at presynaptic terminals, soma, and axons. Ca(V)2.2 channel inhibitors applied to the spinal cord relieve pain in humans and rodents, especially during pathologic pain, but a biological function of nociceptor Ca(V)2.2 channels in p...

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Detalles Bibliográficos
Autores principales: DuBreuil, Daniel M., Lopez Soto, Eduardo Javier, Daste, Simon, Meir, Remy, Li, Daniel, Wainger, Brian, Fleischmann, Alexander, Lipscombe, Diane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425970/
https://www.ncbi.nlm.nih.gov/pubmed/34353899
http://dx.doi.org/10.1523/JNEUROSCI.0195-21.2021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425970/
https://www.ncbi.nlm.nih.gov/pubmed/34353899
http://dx.doi.org/10.1523/JNEUROSCI.0195-21.2021

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