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Heat But Not Mechanical Hypersensitivity Depends on Voltage-Gated Ca(V)2.2 Calcium Channel Activity in Peripheral Axon Terminals Innervating Skin
Voltage-gated Ca(V)2.2 calcium channels are expressed in nociceptors at presynaptic terminals, soma, and axons. Ca(V)2.2 channel inhibitors applied to the spinal cord relieve pain in humans and rodents, especially during pathologic pain, but a biological function of nociceptor Ca(V)2.2 channels in p...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Society for Neuroscience
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425970/ https://www.ncbi.nlm.nih.gov/pubmed/34353899 http://dx.doi.org/10.1523/JNEUROSCI.0195-21.2021 |