Aconitine Induces TRPV2-Mediated Ca(2+) Influx through the p38 MAPK Signal and Promotes Cardiomyocyte Apoptosis

Aconitine is the main effective component of traditional Chinese medicine Aconitum, which has been proved to have severe cardiovascular toxicity. The toxic effect of aconitine on cardiomyocytes is related to intracellular calcium overload, but the mechanism remains unclear. The aim of this study was...

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Detalles Bibliográficos
Autores principales: Yang, Chunai, Zeng, Xiaoyan, Cheng, Zhongfeng, Zhu, Junbo, Fu, Yangshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426055/
https://www.ncbi.nlm.nih.gov/pubmed/34512785
http://dx.doi.org/10.1155/2021/9567056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426055/
https://www.ncbi.nlm.nih.gov/pubmed/34512785
http://dx.doi.org/10.1155/2021/9567056

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