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Aconitine Induces TRPV2-Mediated Ca(2+) Influx through the p38 MAPK Signal and Promotes Cardiomyocyte Apoptosis
Aconitine is the main effective component of traditional Chinese medicine Aconitum, which has been proved to have severe cardiovascular toxicity. The toxic effect of aconitine on cardiomyocytes is related to intracellular calcium overload, but the mechanism remains unclear. The aim of this study was...
Autores principales: | Yang, Chunai, Zeng, Xiaoyan, Cheng, Zhongfeng, Zhu, Junbo, Fu, Yangshan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426055/ https://www.ncbi.nlm.nih.gov/pubmed/34512785 http://dx.doi.org/10.1155/2021/9567056 |
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