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Rapid and stable mobilization of CD8(+) T cells by SARS-CoV-2 mRNA vaccine

SARS-CoV-2 spike mRNA vaccines(1–3) mediate protection from severe disease as early as ten days after prime vaccination(3), when neutralizing antibodies are hardly detectable(4–6). Vaccine-induced CD8(+) T cells may therefore be the main mediators of protection at this early stage(7,8). The details...

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Detalles Bibliográficos
Autores principales: Oberhardt, Valerie, Luxenburger, Hendrik, Kemming, Janine, Schulien, Isabel, Ciminski, Kevin, Giese, Sebastian, Csernalabics, Benedikt, Lang-Meli, Julia, Janowska, Iga, Staniek, Julian, Wild, Katharina, Basho, Kristi, Marinescu, Mircea Stefan, Fuchs, Jonas, Topfstedt, Fernando, Janda, Ales, Sogukpinar, Oezlem, Hilger, Hanna, Stete, Katarina, Emmerich, Florian, Bengsch, Bertram, Waller, Cornelius F., Rieg, Siegbert, Sagar, Boettler, Tobias, Zoldan, Katharina, Kochs, Georg, Schwemmle, Martin, Rizzi, Marta, Thimme, Robert, Neumann-Haefelin, Christoph, Hofmann, Maike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426185/
https://www.ncbi.nlm.nih.gov/pubmed/34320609
http://dx.doi.org/10.1038/s41586-021-03841-4