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The interaction of Epstein-Barr virus encoded transcription factor EBNA2 with multiple sclerosis risk loci is dependent on the risk genotype

BACKGROUND: Epstein-Barr virus (EBV) infection may be necessary for the development of Multiple sclerosis (MS). Earlier we had identified six MS risk loci that are co-located with binding sites for the EBV transcription factor Epstein-Barr Nuclear Antigen 2 (EBNA2) in EBV-infected B cells (lymphobla...

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Detalles Bibliográficos
Autores principales: Keane, Jeremy Thomas, Afrasiabi, Ali, Schibeci, Stephen Donald, Swaminathan, Sanjay, Parnell, Grant Peter, Booth, David Richmond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426200/
https://www.ncbi.nlm.nih.gov/pubmed/34488019
http://dx.doi.org/10.1016/j.ebiom.2021.103572