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Phase I first-in-human study of HLX07, a novel and improved recombinant anti-EGFR humanized monoclonal antibody, in patients with advanced solid cancers

Purpose This study aimed to evaluate the safety and pharmacokinetic (PK) profiles of HLX07, a novel, recombinant, humanized anti-epidermal growth factor receptor (EGFR) antibody, in patients with advanced solid cancers who had failed standard therapy or for whom no standard therapy was available. Me...

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Detalles Bibliográficos
Autores principales: Hou, Ming-Mo, Ho, Ching-Liang, Lin, Hsuan-Yu, Zhu, Yunting, Zhang, Xiaodi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426222/
https://www.ncbi.nlm.nih.gov/pubmed/33713216
http://dx.doi.org/10.1007/s10637-021-01099-1