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The Trithorax group protein ASH1 requires a combination of BAH domain and AT hooks, but not the SET domain, for mitotic chromatin binding and survival

The Drosophila Trithorax group (TrxG) protein ASH1 remains associated with mitotic chromatin through mechanisms that are poorly understood. ASH1 dimethylates histone H3 at lysine 36 via its SET domain. Here, we identify domains of the TrxG protein ASH1 that are required for mitotic chromatin attachm...

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Detalles Bibliográficos
Autores principales: Steffen, Philipp A., Altmutter, Christina, Dworschak, Eva, Junttila, Sini, Gyenesei, Attila, Zhu, Xinzhou, Kockmann, Tobias, Ringrose, Leonie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426247/
https://www.ncbi.nlm.nih.gov/pubmed/34331109
http://dx.doi.org/10.1007/s00412-021-00762-z