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The Trithorax group protein ASH1 requires a combination of BAH domain and AT hooks, but not the SET domain, for mitotic chromatin binding and survival
The Drosophila Trithorax group (TrxG) protein ASH1 remains associated with mitotic chromatin through mechanisms that are poorly understood. ASH1 dimethylates histone H3 at lysine 36 via its SET domain. Here, we identify domains of the TrxG protein ASH1 that are required for mitotic chromatin attachm...
Autores principales: | Steffen, Philipp A., Altmutter, Christina, Dworschak, Eva, Junttila, Sini, Gyenesei, Attila, Zhu, Xinzhou, Kockmann, Tobias, Ringrose, Leonie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426247/ https://www.ncbi.nlm.nih.gov/pubmed/34331109 http://dx.doi.org/10.1007/s00412-021-00762-z |
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