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PD-1-stimulated T cell subsets are transcriptionally and functionally distinct

Despite the obvious inhibitory outcome of PD-1 signaling, an additional series of functions are activated. We have observed that T cells stimulated through the T cell receptor (TCR) and PD-1 primarily do not proliferate; however, there is a population of cells that proliferates more than through TCR...

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Detalles Bibliográficos
Autores principales: Lerrer, Shalom, Tocheva, Anna S., Bukhari, Shoiab, Adam, Kieran, Mor, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426269/
https://www.ncbi.nlm.nih.gov/pubmed/34522863
http://dx.doi.org/10.1016/j.isci.2021.103020