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PD-1-stimulated T cell subsets are transcriptionally and functionally distinct
Despite the obvious inhibitory outcome of PD-1 signaling, an additional series of functions are activated. We have observed that T cells stimulated through the T cell receptor (TCR) and PD-1 primarily do not proliferate; however, there is a population of cells that proliferates more than through TCR...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426269/ https://www.ncbi.nlm.nih.gov/pubmed/34522863 http://dx.doi.org/10.1016/j.isci.2021.103020 |