Cargando…

Pulmonary infection induces persistent, pathogen-specific lipidomic changes influencing trained immunity

Resolution of infection results in development of trained innate immunity which is typically beneficial for defense against unrelated secondary infection. Epigenetic changes including modification of histones via binding of various polar metabolites underlie the establishment of trained innate immun...

Descripción completa

Detalles Bibliográficos
Autores principales: Roberts, Lydia M., Schwarz, Benjamin, Speranza, Emily, Leighton, Ian, Wehrly, Tara, Best, Sonja, Bosio, Catharine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426275/
https://www.ncbi.nlm.nih.gov/pubmed/34522865
http://dx.doi.org/10.1016/j.isci.2021.103025