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Pulmonary infection induces persistent, pathogen-specific lipidomic changes influencing trained immunity
Resolution of infection results in development of trained innate immunity which is typically beneficial for defense against unrelated secondary infection. Epigenetic changes including modification of histones via binding of various polar metabolites underlie the establishment of trained innate immun...
Autores principales: | Roberts, Lydia M., Schwarz, Benjamin, Speranza, Emily, Leighton, Ian, Wehrly, Tara, Best, Sonja, Bosio, Catharine M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426275/ https://www.ncbi.nlm.nih.gov/pubmed/34522865 http://dx.doi.org/10.1016/j.isci.2021.103025 |
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