Cellular senescence promotes cancer metastasis by enhancing soluble E-cadherin production

Cellular senescence acts as a potent tumor-suppression mechanism in mammals; however, it also promotes tumor progression in a non-cell-autonomous manner. We provided insights into the mechanism underlying senescence-dependent metastatic cancer development. The elimination of senescent cells suppress...

Descripción completa

Detalles Bibliográficos
Autores principales: Kawaguchi, Koichiro, Komoda, Kaori, Mikawa, Ryuta, Asai, Azusa, Sugimoto, Masataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426284/
https://www.ncbi.nlm.nih.gov/pubmed/34522864
http://dx.doi.org/10.1016/j.isci.2021.103022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426284/
https://www.ncbi.nlm.nih.gov/pubmed/34522864
http://dx.doi.org/10.1016/j.isci.2021.103022

Ejemplares similares