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Cellular senescence promotes cancer metastasis by enhancing soluble E-cadherin production

Cellular senescence acts as a potent tumor-suppression mechanism in mammals; however, it also promotes tumor progression in a non-cell-autonomous manner. We provided insights into the mechanism underlying senescence-dependent metastatic cancer development. The elimination of senescent cells suppress...

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Detalles Bibliográficos
Autores principales:	Kawaguchi, Koichiro, Komoda, Kaori, Mikawa, Ryuta, Asai, Azusa, Sugimoto, Masataka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426284/ https://www.ncbi.nlm.nih.gov/pubmed/34522864 http://dx.doi.org/10.1016/j.isci.2021.103022

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